Caleva Knowledge Base

Formulation development with Caleva

Written by Caleva | 28-Apr-2021 10:50:38

The process of spheronization consists of four key steps:-

  • To optimize and achieve the right binder addition  & mixing time for your formulation
  • Mixing or granulation - a mixer or granulator is required
  • Extrusion - an extruder is required
  • Spheronization - a spheronizer is required
  • Drying and possibly coating - a coater and drier may be required

This is all made simple by the Caleva suite of R&D equipment shown in the section below.

Quantify the Characteristics of your Formulation

  • Reduce your formulation development time
  • Optimize the characteristics of your formulation?
  • Can you confirm that the same product from different suppliers behaves differently in your formulations?
  • Would it be useful to be able to quantify the characteristics of samples taken from your granulator?

Mixer Torque Rheometer

 

Mix, Extrude, Spheronize and Analyse with a Single Bench-Top Unit

  • Save benchtop space, time and materials with small batch sizes of 10 - 40 g
  • Fast processing times means you can go from powder to pellets in 20 minutes or less 
  • Various bowls, blades, extruder screws, barrels, and die options available for different materials
  • Multi Lab Classic's software and accessories can be upgraded after purchase to the Multi Lab Scientific 
  • Multi Lab Scientific has automated data acquisition, recipe management and automatic operation, motor load % reports, temperature monitoring and data export for in-depth analysis.

Multi Lab Scientific

 

Quickly Coat or Dry a Few Tablets, Capsules or Pellets

  • From a single tablet up to about 50 tablets
  • From a few grams to about 60 grams of small pellets 
  • From a single capsule to a "small handful" of pellets
  • You can reduce the amounts of ingredients used whilst still producing meaningful results

Mini Coater Dryer