Back

Can I modify the density of extrudate produced during extrusion?

During the formulation development process, challenges related to final product performance have to be examined, exposed and overcome.

This is not always easy or straight-forward. However, if you have more options that you can investigate then there is likely to be an increased probability of a successful result.   Different factors are considered as part of any formulation development and these are as varied as the different formulation methods and equipment used. In practise not all options can be tried and selections will be made.

Can I extrude product with different densities as a routine part of product formulation development trials?  

 

 

Some of the key factors in any program to reach an optimum formulation would be combinations of:
 
  • Physical and chemical properties of the active materials as well as its availability and cost
  • The results required (costs, ease of scale up, final product properties and performance)
  • Your equipment and it's capabilities
  • The development time available (and therefore the number of trial iterations that can be completed)

 

The Caleva Multi Lab is designed with these concepts in mind and uniquely offers benefits to researchers that respond to the challenges listed above.

Caleva-Multi-Lab-training-in-variable-density-extrusion-in-the-Caleva-training-laboratory

 

 

 

 

 

 

 

 

 

 

Is your product scarce or expensive?

Question:
Are you developing new formulations with limited amounts of product?

Answer:
The Caleva CML offers you the ability to work with small samples (around 50 g wet weight or less)

 

Is your time for trial work limited?

Question:
Do you need results as quickly as possible to complete more trial iterations in a working day?

Answer:
See how the CML offers the fastest trial throughput available enabling a significant increase in productivity

 

Extruding at different densities

Question:
Do you know if extruding your product at different pressures will result in the final product having different physical properties?

Answer:
Find out by looking at what the CML offers.

 

 

Dr Steve Robinson
By Dr Steve Robinson
29 Oct 2020 in Variable Density Extrusion

Leave A Comment

Talk To Caleva

How to Reduce Your Formulation Development Time

Discover how to cut your formulation development time in half with the Caleva Multi Lab and its wide range of variable density dies. Read More

Do I Need a Screen Extruder or a Screw Extruder?

At Caleva, we offer a variety of extruders to meet your needs, from laboratory scale extruders for research and development purposes, to pilot scale extruders and larger models for batch production environments. Read More

Extrusion of small batches

The Caleva Multi-Lab (CML) can Mix/Granulate, Extrude and Spheronize all in one base unit. This article is about the Extruder attachment that comes with the CML. The Multi-lab is capable of working with a variety of materials from catalysts and pharmaceuticals, to agricultural products. The Extruder... Read More

Possible issues with extrusion of small samples - how to resolve them

It is not possible to extrude and spheronize everything. Extrusion and spheronization can be used on a wide range of products and formulations. However, if you are having trouble extruding your formulations with the Caleva Multi Lab (CML) then please read this article. Caleva offers extruder screws ... Read More

Extruder dies | all sizes | variable density | quadrilobe | trilobe

In the process of extrusion, having different dies available to process your product is key to increasing your chances of development success. This is why we offer a large range of dies to help you find the best options for your formulation. We offer die plates that are excellent for most uses, like... Read More

Extrusion of catalyst and petrochemical materials

An opportunity in laboratory extrusion with catalyst material. We have recently had some considerable success with one of our customers working with the extrusion of small quantities of catalytic material. Read More

Extruding catalyst materials for petrochemical and adsorption products

Using the Caleva Multi Lab it is possible to extrude of small quantities of catalytic material, whilst increasing the surface area to volume ratio of the extrudate produced. Read More

Guide to the optimum diameter to length ratio of extrudate fragments

Is there a guide to the optimum Length to Diameter ratio of the extrudate fragments? In the calculations used to demonstrate the data it is assumed that the extrudate is an infinitely long strand. In this case the length of the extrudate has no influence on the data shown. In reality, extrudate is n... Read More

What type of pharmaceutical or catalyst extruder do I need?

All extrusion processes require the generation of pressure within the material to be extruded. When materials are put under pressure heat is generated. This cannot be avoided but different extrusion types generate different amounts of heat. There are basically three different types of extruder and t... Read More

Increase the Surface Area to Volume Ratio in the Extruded Material

Can the equipment design help to increase the surface area to volume ratio (SA/V) in the extruded material (extrudate)? Read More

Modify the density, pore size and porosity of the extruded material

The Caleva CML extruder attachment is the smallest in the family of screw driven extruders that can offer the operator the ability to extrude the material at high, medium high, medium low, or low density. By management of the extrudate density physical properties of the extruded material can be infl... Read More

Can I modify the density of extrudate produced during extrusion?

During the formulation development process, challenges related to final product performance have to be examined, exposed and overcome. This is not always easy or straight-forward. However, if you have more options that you can investigate then there is likely to be an increased probability of a succ... Read More

Is there a correctly sized extruder die to get the size of pellets you need?

There is no simple answer to this question as it depends on the characteristics of your formulation and the size of the pellets you require. Read More

How can I be sure that the trials and development work that I do will give me comparable results when I need to scale up to production sizes?

Scale up of the spheronization process is relatively well known and understood. All of the Caleva extrusion and spheronization equipment is designed with scale up in mind. Our range of screw extruders have the ability to modify the density of your extrudate when this is important. The smallest extru... Read More